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Relfydess

Experience the next generation of anti-wrinkle treatments. Relfydess is the first fully vegan botulinum toxin—delivering visible results in days, not weeks, with effects lasting 3-4 weeks longer than traditional injections. Galderma’s latest innovation combines faster action, extended duration, and plant-based formulation for the future of facial aesthetics.

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TREATMENT SUMMARY

Procedure time
10 - 15mins
Recovery time
Immediate
Duration of results
4-5 months
Sessions required
Single session, repeated as needed
Treatment areas
Frown lines, forehead, crow's feet
Discomfort level
Minimal

What is Relfydess?

Relfydess (relabotulinumtoxinA) is Galderma’s newest botulinum toxin type A formulation, approved for use in Europe for the temporary improvement of moderate to severe glabellar lines (frown lines between the eyebrows).

Developed through advanced protein engineering, Relfydess offers a fresh approach to facial rejuvenation with distinct characteristics that set it apart from established anti-wrinkle treatments. The treatment works by temporarily relaxing the facial muscles responsible for dynamic wrinkles—those lines that form when you frown, squint, or raise your eyebrows.

Clinical studies show Relfydess has a quicker onset of action and lasts 3-4 weeks longer than existing formulations. As a fully vegan product with no human or animal-derived proteins, it represents a significant advancement for patients seeking plant-based aesthetic treatments.

At Dr MediSpa, our award-winning practitioners serve as Key Opinion Leaders (KOLs) for Galderma and are among the first in the UK to offer this innovative treatment across our London and Essex clinics, delivering natural, refined results with the latest technology available.

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Reviews

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Debra Wilkinson profile picture
Debra Wilkinson
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I am halfway through my treatment programme but so far very happy with the results and service. I have made a big financial commitment but after initial consultations, feel well informed and believe my expectations have been managed appropriately. Everyone in the salon is very friendly and helpful and I feel comfortable and well looked after when I'm there. Ellie is very knowledgeable and thorough. Would highly recommend.
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Janan Shakir profile picture
Janan Shakir
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Absolutely love this clinic. Lucia is a star. Wouldn’t go anywhere else
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Suela Kordhaku profile picture
Suela Kordhaku
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The only place I trust with my face. I’m quite particular and have a medical background, so I don’t say that lightly. Everything is done properly, with care and precision, never rushed. Ellie is incredibly thorough and consistent, and Olaya has genuinely helped me get my confidence and my skin back. Professional, honest, and results-driven. I wouldn’t go anywhere else.
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Carina Bartle profile picture
Carina Bartle
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I have been seeing Dr Somji regularly and exclusively for 10 years (usually every 3/5 months) and have always trusted his expertise I can honestly say he is the best. His clinic team also are fantastic. Last week I had a fire and ice facial with Mariana, it left me glowing and I also had a nice skin care lesson from Mariana, she was very knowledgable and it is certainly a treatment I would book again. Thank you to all the team
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Annette Machon profile picture
Annette Machon
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I’ve always felt very comfortable visiting DrMediSpa. Dr Somji is extremely knowledgeable and professional and the staff are welcoming, friendly, kind and courteous. It’s always obvious that the clinic is a lovely working environment for the staff and would recommend the clinic 100%. I wouldn’t dream of going anywhere else
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Milan Shah profile picture
Milan Shah
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Great experience with Dr Munirs guidance, Dr Bhavik Shahs expertise and Claudia who performed the treatment for Dye IPL and Ipixel. The journey was carefully thought out and was a lot less painful than I thought. Thank you all at Dr Medispa!
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Maria Goodspeed profile picture
Maria Goodspeed
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I always enjoy visiting Dr MediSpa! The staff are incredibly friendly and welcoming, making every appointment a great experience. They take the time to understand my needs and always recommend the best treatments. I trust their expertise completely and always leave feeling refreshed and confident. Highly recommend!
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Accounting and Tax Academy by Tony D
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Fantastic :-) I visited Dr Somji's mid 2025, and through a robust, transparent and consultative process, received treatment for my alopecia. After approximately 5 months from my first round of treatment, there are visible signs of my hair growing back A big shout out to Amz Dhanjal at the front desk for co-ordinating (and buying me a cup of tea from Gails)
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LEILY BANAN profile picture
LEILY BANAN
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I see Dr somji and Elli today. I loveee Somji and his lovey wife Henal I've been coming to the clinic for 6-7 years now and super happy with every visit and results. My sister comes here too and alway so happy. I'm in the industry myself and wouldn't go anywhere else highly recommend
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Emily profile picture
Emily
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I am very impressed with this Clinic. I am so happy with my Lip filler treatments from the very talented and artistic injector Dr Somji, who provided me with NATURAL results! He is very thorough, and won’t do any treatments he doesn’t think are necessary, he actually persuaded me to have less! During the consultation I was educated on all the risks, pros and cons, and measured my facial proportions to work out exactly what was best to suit my face naturally. His theory is ‘less is more’ and I completely agree! I went in thinking I needed jawline filler, lip filler, cheek filler and Botox which is what I’ve been told by other places, being ‘sold too’, in fact all I needed was a touch of lip and chin filler to balance my symmetry and this was absolutely perfect! He’s a master at the Cannula method, I felt minimal discomfort, had 0 bruising because the tip is blunt and my anxiety of injectables is now much less as I now know this is the safest method. I couldn’t recommend Dr Somji any more, professional, patient, understanding, safe and a master Injector! The Drs assistant Elli was very sweet too making sure I felt comfortable through out, embarrassingly held my hand to calm my nerves which I might add really helped! 5 stars!!!!

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Am I suitable for Relfydess?

Relfydess is suitable for most healthy adults aged 18-65 who want to reduce moderate to
severe frown lines. However, it's not appropriate during pregnancy or breastfeeding, or for
people with certain neuromuscular conditions. A consultation is essential to determine
suitability and ensure this is the right treatment for your needs.
How

How does Relfydess compare to traditional anti-wrinkle treatments?

Relfydess uses newer recombinant technology and clinical studies show it has a quicker onset of action—often within 2-4 days compared to 7-14 days for traditional products. Importantly, results last 3-4 weeks longer than existing formulations, giving you 4-5 months of results instead of the typical 3-4 months. Relfydess is also fully vegan, containing no human or animal-derived proteins, making it the first plant-based botulinum toxin option available.

What happens during the treatment?

Your skin will be cleansed and topical numbing may be applied if desired. Precise injections are then placed in predetermined points based on your facial anatomy and treatment goals.
The entire procedure takes just 10-15 minutes, and you can return to normal activities immediately afterwards.

Does Relfydess hurt?

Most patients describe the sensation as a quick pinch or mild stinging. The needles used are very fine, and we can apply topical numbing cream if you're concerned about discomfort. The treatment itself takes only 10-15 minutes.

When will I see results from Relfydess?

You may notice initial improvements within 2-4 days, with full results developing over 7-14 days. This faster onset is one of Relfydess's key advantages over traditional products. We schedule a review appointment 2-3 weeks after treatment to assess results.

How long do Relfydess results last?

Clinical studies demonstrate that Relfydess results last 4-5 months—approximately 3-4 weeks longer than traditional botulinum toxin products. Individual results vary based on factors including your metabolism, muscle strength, lifestyle, and the amount of product used. You can return for maintenance treatments as needed.

What is the recovery time?

There’s no downtime required. You should avoid lying flat for 4 hours post-treatment and avoid strenuous exercise for 24 hours. Some patients experience slight bruising, swelling, or redness at injection sites, but these are typically mild and temporary.

Can I combine Relfydess with other treatments?

Yes, Relfydess can be combined with dermal fillers, skin resurfacing treatments, and other aesthetic procedures. In fact, combination approaches often produce the most comprehensive results. We'll discuss the optimal treatment sequence during your consultation.

What are the benefits of Relfydess?

Relfydess offers rapid onset of visible results (within 2-4 days), longer-lasting results (4-5 months, which is 3-4 weeks longer than traditional products), fully vegan formulation with no human or animal-derived proteins, natural-looking outcomes that preserve facial expressiveness, and a comparable safety profile to established products. The molecular structure has been engineered for precision and extended duration.

How much does Relfydess cost?

Treatment costs vary based on the areas treated and amount of product required. As a guide: single area (frown lines) from £250, two areas from £350, three areas from £450. We provide transparent pricing during your consultation based on your specific needs.

Why choose Dr MediSpa for Relfydess?

Dr MediSpa's practitioners serve as Key Opinion Leaders (KOLs) for Galderma, providing expert-level knowledge and experience with the latest injectable innovations. We’ve been recognized with multiple industry awards and have built a reputation for clinical excellence.
Our practitioners deliver safe, effective treatments with natural-looking results. Unlike clinics that focus solely on injectables, we offer the full spectrum of advanced aesthetic treatments across our three convenient locations in Marylebone, Knightsbridge, and Loughton.

Can Sculptra Body be combined with other treatments?

Yes, Sculptra Body can be combined with other body contouring treatments for enhanced results. Popular combinations include EMSculpt NEO for muscle toning alongside volume restoration, Morpheus8 Body for skin tightening and texture improvement, laser treatments for skin tone and texture, and targeted fat reduction treatments. Your practitioner will recommend the optimal treatment combination for your goals.

Why choose Dr Medispa

24/7 Doctor care after your treatment
Appointments to suit you including evenings and weekends
Registered with the Care Quality Commission (CQC)
Full member of the British College of Aesthetic Medicine (BCAM)
Team of highly-qualified doctors
Range of payment options available

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